Deploy Microsoft Sentinel as a cloud-native SIEM/SOAR by configuring multi-cloud data connectors (AWS, Azure, GCP), writing KQL detection and hunting queries, and building automated Logic Apps response playbooks. Use when establishing a centralized SOC for multi-cloud environments, migrating from a legacy SIEM, or performing petabyte-scale threat hunting; not for AWS-only setups where Security Hub/GuardDuty suffice or for endpoint EDR needs.